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Functional screen identifies regulators of murine hematopoietic stem cell repopulation

Understanding the molecular regulation of hematopoietic stem and progenitor cell (HSPC) engraftment is paramount to improving transplant outcomes. To discover novel regulators of HSPC repopulation, we transplanted >1,300 mice with shRNA-transduced HSPCs within 24 h of isolation and transduction t...

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Detalles Bibliográficos
Autores principales:	Holmfeldt, Per, Ganuza, Miguel, Marathe, Himangi, He, Bing, Hall, Trent, Kang, Guolian, Moen, Joseph, Pardieck, Jennifer, Saulsberry, Angelica C., Cico, Alba, Gaut, Ludovic, McGoldrick, Daniel, Finkelstein, David, Tan, Kai, McKinney-Freeman, Shannon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2016
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4813668/ https://www.ncbi.nlm.nih.gov/pubmed/26880577 http://dx.doi.org/10.1084/jem.20150806

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