The glycolytic enzyme PKM2 bridges metabolic and inflammatory dysfunction in coronary artery disease

Abnormal glucose metabolism and enhanced oxidative stress accelerate cardiovascular disease, a chronic inflammatory condition causing high morbidity and mortality. Here, we report that in monocytes and macrophages of patients with atherosclerotic coronary artery disease (CAD), overutilization of glu...

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Detalles Bibliográficos
Autores principales: Shirai, Tsuyoshi, Nazarewicz, Rafal R., Wallis, Barbara B., Yanes, Rolando E., Watanabe, Ryu, Hilhorst, Marc, Tian, Lu, Harrison, David G., Giacomini, John C., Assimes, Themistocles L., Goronzy, Jörg J., Weyand, Cornelia M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2016
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4813677/
https://www.ncbi.nlm.nih.gov/pubmed/26926996
http://dx.doi.org/10.1084/jem.20150900

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