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Pathology Tissue-quantitative Mass Spectrometry Analysis to Profile Histone Post-translational Modification Patterns in Patient Samples

Histone post-translational modifications (hPTMs) generate a complex combinatorial code that has been implicated with various pathologies, including cancer. Dissecting such a code in physiological and diseased states may be exploited for epigenetic biomarker discovery, but hPTM analysis in clinical s...

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Detalles Bibliográficos
Autores principales: Noberini, Roberta, Uggetti, Andrea, Pruneri, Giancarlo, Minucci, Saverio, Bonaldi, Tiziana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Biochemistry and Molecular Biology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4813706/
https://www.ncbi.nlm.nih.gov/pubmed/26463340
http://dx.doi.org/10.1074/mcp.M115.054510