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Comparison of biological activities of human antithrombins with high-mannose or complex-type nonfucosylated N-linked oligosaccharides

The structure of the N-linked oligosaccharides attached to antithrombin (AT) has been shown to affect its anticoagulant activity and pharmacokinetics. Human AT has biantennary complex-type oligosaccharides with the unique feature of lacking a core fucose, which affects its biological activities by c...

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Detalles Bibliográficos
Autores principales:	Yamada, Tsuyoshi, Kanda, Yutaka, Takayama, Makoto, Hashimoto, Akitoshi, Sugihara, Tsutomu, Satoh-Kubota, Ai, Suzuki-Takanami, Eri, Yano, Keiichi, Iida, Shigeru, Satoh, Mitsuo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2016
Materias:	ORIGINAL ARTICLES
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4813732/ https://www.ncbi.nlm.nih.gov/pubmed/26747427 http://dx.doi.org/10.1093/glycob/cww001

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