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Modulation of Matrix Metalloproteinases Activity in the Ventral Horn of the Spinal Cord Re-stores Neuroglial Synaptic Homeostasis and Neurotrophic Support following Peripheral Nerve Injury
Modulation of extracellular matrix (ECM) remodeling after peripheral nerve injury (PNI) could represent a valid therapeutic strategy to prevent maladaptive synaptic plasticity in central nervous system (CNS). Inhibition of matrix metalloproteinases (MMPs) and maintaining a neurotrophic support could...
Autores principales: | Cirillo, Giovanni, Colangelo, Anna Maria, De Luca, Ciro, Savarese, Leonilde, Barillari, Maria Rosaria, Alberghina, Lilia, Papa, Michele |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4814041/ https://www.ncbi.nlm.nih.gov/pubmed/27028103 http://dx.doi.org/10.1371/journal.pone.0152750 |
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