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Assessing Concordance of Drug-Induced Transcriptional Response in Rodent Liver and Cultured Hepatocytes

The effect of drugs, disease and other perturbations on mRNA levels are studied using gene expression microarrays or RNA-seq, with the goal of understanding molecular effects arising from the perturbation. Previous comparisons of reproducibility across laboratories have been limited in scale and foc...

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Detalles Bibliográficos
Autores principales:	Sutherland, Jeffrey J., Jolly, Robert A., Goldstein, Keith M., Stevens, James L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4814051/ https://www.ncbi.nlm.nih.gov/pubmed/27028627 http://dx.doi.org/10.1371/journal.pcbi.1004847

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