Cargando…
The Hemagglutinin of Bat-Associated Influenza Viruses Is Activated by TMPRSS2 for pH-Dependent Entry into Bat but Not Human Cells
New World bats have recently been discovered to harbor influenza A virus (FLUAV)-related viruses, termed bat-associated influenza A-like viruses (batFLUAV). The internal proteins of batFLUAV are functional in mammalian cells. In contrast, no biological functionality could be demonstrated for the sur...
Autores principales: | Hoffmann, Markus, Krüger, Nadine, Zmora, Pawel, Wrensch, Florian, Herrler, Georg, Pöhlmann, Stefan |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4814062/ https://www.ncbi.nlm.nih.gov/pubmed/27028521 http://dx.doi.org/10.1371/journal.pone.0152134 |
Ejemplares similares
-
TMPRSS11A activates the influenza A virus hemagglutinin and the MERS coronavirus spike protein and is insensitive against blockade by HAI-1
por: Zmora, Pawel, et al.
Publicado: (2018) -
SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor
por: Hoffmann, Markus, et al.
Publicado: (2020) -
Non-human primate orthologues of TMPRSS2 cleave and activate the influenza virus hemagglutinin
por: Zmora, Pawel, et al.
Publicado: (2017) -
The Glycoproteins of All Filovirus Species Use the Same Host Factors for Entry into Bat and Human Cells but Entry Efficiency Is Species Dependent
por: Hoffmann, Markus, et al.
Publicado: (2016) -
Comparative Analysis of Ebola Virus Glycoprotein Interactions With Human and Bat Cells
por: Kühl, Annika, et al.
Publicado: (2011)