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Cystatin C as a p53‐inducible apoptotic mediator that regulates cathepsin L activity

In response to various cellular stresses, p53 is activated and inhibits malignant transformation through the transcriptional regulation of its target genes. However, the full picture of the p53 downstream pathway still remains to be elucidated. Here we identified cystatin C, a major inhibitor of cat...

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Detalles Bibliográficos
Autores principales: Mori, Jinichi, Tanikawa, Chizu, Funauchi, Yuki, Lo, Paulisally Hau Yi, Nakamura, Yusuke, Matsuda, Koichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4814261/
https://www.ncbi.nlm.nih.gov/pubmed/26757339
http://dx.doi.org/10.1111/cas.12881