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Specific transport of 3‐fluoro‐l‐α‐methyl‐tyrosine by LAT1 explains its specificity to malignant tumors in imaging

3‐(18)F‐l‐α‐methyl‐tyrosine ([(18)F]FAMT), a PET probe for tumor imaging, has advantages of high cancer‐specificity and lower physiologic background. FAMT‐PET has been proved useful in clinical studies for the prediction of prognosis, the assessment of therapy response and the differentiation of mal...

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Detalles Bibliográficos
Autores principales: Wei, Ling, Tominaga, Hideyuki, Ohgaki, Ryuichi, Wiriyasermkul, Pattama, Hagiwara, Kohei, Okuda, Suguru, Kaira, Kyoichi, Oriuchi, Noboru, Nagamori, Shushi, Kanai, Yoshikatsu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4814262/
https://www.ncbi.nlm.nih.gov/pubmed/26749017
http://dx.doi.org/10.1111/cas.12878