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Unique chloride-sensing properties of WNK4 permit the distal nephron to modulate potassium homeostasis

Dietary potassium deficiency activates thiazide-sensitive sodium chloride cotransport along the distal nephron. This may explain, in part, the hypertension and cardiovascular mortality observed in individuals who consume a low potassium diet. Recent data suggest plasma potassium affects the distal n...

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Detalles Bibliográficos
Autores principales:	Terker, Andrew S., Zhang, Chong, Erspamer, Kayla J., Gamba, Gerardo, Yang, Chao-Ling, Ellison, David H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4814375/ https://www.ncbi.nlm.nih.gov/pubmed/26422504 http://dx.doi.org/10.1038/ki.2015.289

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