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Interaction of the Oncofetal Thomsen–Friedenreich Antigen with Galectins in Cancer Progression and Metastasis

Aberrant glycosylation of cell membrane proteins is a universal feature of cancer cells. One of the most common glycosylation changes in epithelial cancer is the increased occurrence of the oncofetal Thomsen–Friedenreich disaccharide Galβ1–3GalNAc (T or TF antigen), which appears in about 90% of can...

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Detalles Bibliográficos
Autores principales: Sindrewicz, Paulina, Lian, Lu-Yun, Yu, Lu-Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4814717/
https://www.ncbi.nlm.nih.gov/pubmed/27066458
http://dx.doi.org/10.3389/fonc.2016.00079