Structure Based Docking and Molecular Dynamic Studies of Plasmodial Cysteine Proteases against a South African Natural Compound and its Analogs

Identification of potential drug targets as well as development of novel antimalarial chemotherapies with unique mode of actions due to drug resistance by Plasmodium parasites are inevitable. Falcipains (falcipain-2 and falcipain-3) of Plasmodium falciparum, which catalyse the haemoglobin degradatio...

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Detalles Bibliográficos
Autores principales: Musyoka, Thommas M., Kanzi, Aquillah M., Lobb, Kevin A., Tastan Bishop, Özlem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4814779/
https://www.ncbi.nlm.nih.gov/pubmed/27030511
http://dx.doi.org/10.1038/srep23690

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4814779/
https://www.ncbi.nlm.nih.gov/pubmed/27030511
http://dx.doi.org/10.1038/srep23690

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