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Emotion-induced loss aversion and striatal-amygdala coupling in low-anxious individuals

Adapting behavior to changes in the environment is a crucial ability for survival but such adaptation varies widely across individuals. Here, we asked how humans alter their economic decision-making in response to emotional cues, and whether this is related to trait anxiety. Developing an emotional...

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Autores principales: Charpentier, Caroline J., Martino, Benedetto De, Sim, Alena L., Sharot, Tali, Roiser, Jonathan P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4814785/
https://www.ncbi.nlm.nih.gov/pubmed/26589451
http://dx.doi.org/10.1093/scan/nsv139
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author Charpentier, Caroline J.
Martino, Benedetto De
Sim, Alena L.
Sharot, Tali
Roiser, Jonathan P.
author_facet Charpentier, Caroline J.
Martino, Benedetto De
Sim, Alena L.
Sharot, Tali
Roiser, Jonathan P.
author_sort Charpentier, Caroline J.
collection PubMed
description Adapting behavior to changes in the environment is a crucial ability for survival but such adaptation varies widely across individuals. Here, we asked how humans alter their economic decision-making in response to emotional cues, and whether this is related to trait anxiety. Developing an emotional decision-making task for functional magnetic resonance imaging, in which gambling decisions were preceded by emotional and non-emotional primes, we assessed emotional influences on loss aversion, the tendency to overweigh potential monetary losses relative to gains. Our behavioral results revealed that only low-anxious individuals exhibited increased loss aversion under emotional conditions. This emotional modulation of decision-making was accompanied by a corresponding emotion-elicited increase in amygdala-striatal functional connectivity, which correlated with the behavioral effect across participants. Consistent with prior reports of ‘neural loss aversion’, both amygdala and ventral striatum tracked losses more strongly than gains, and amygdala loss aversion signals were exaggerated by emotion, suggesting a potential role for this structure in integrating value and emotion cues. Increased loss aversion and striatal-amygdala coupling induced by emotional cues may reflect the engagement of adaptive harm-avoidance mechanisms in low-anxious individuals, possibly promoting resilience to psychopathology.
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spelling pubmed-48147852016-04-04 Emotion-induced loss aversion and striatal-amygdala coupling in low-anxious individuals Charpentier, Caroline J. Martino, Benedetto De Sim, Alena L. Sharot, Tali Roiser, Jonathan P. Soc Cogn Affect Neurosci Original Articles Adapting behavior to changes in the environment is a crucial ability for survival but such adaptation varies widely across individuals. Here, we asked how humans alter their economic decision-making in response to emotional cues, and whether this is related to trait anxiety. Developing an emotional decision-making task for functional magnetic resonance imaging, in which gambling decisions were preceded by emotional and non-emotional primes, we assessed emotional influences on loss aversion, the tendency to overweigh potential monetary losses relative to gains. Our behavioral results revealed that only low-anxious individuals exhibited increased loss aversion under emotional conditions. This emotional modulation of decision-making was accompanied by a corresponding emotion-elicited increase in amygdala-striatal functional connectivity, which correlated with the behavioral effect across participants. Consistent with prior reports of ‘neural loss aversion’, both amygdala and ventral striatum tracked losses more strongly than gains, and amygdala loss aversion signals were exaggerated by emotion, suggesting a potential role for this structure in integrating value and emotion cues. Increased loss aversion and striatal-amygdala coupling induced by emotional cues may reflect the engagement of adaptive harm-avoidance mechanisms in low-anxious individuals, possibly promoting resilience to psychopathology. Oxford University Press 2016-04 2015-11-19 /pmc/articles/PMC4814785/ /pubmed/26589451 http://dx.doi.org/10.1093/scan/nsv139 Text en © The Author (2015). Published by Oxford University Press. http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Articles
Charpentier, Caroline J.
Martino, Benedetto De
Sim, Alena L.
Sharot, Tali
Roiser, Jonathan P.
Emotion-induced loss aversion and striatal-amygdala coupling in low-anxious individuals
title Emotion-induced loss aversion and striatal-amygdala coupling in low-anxious individuals
title_full Emotion-induced loss aversion and striatal-amygdala coupling in low-anxious individuals
title_fullStr Emotion-induced loss aversion and striatal-amygdala coupling in low-anxious individuals
title_full_unstemmed Emotion-induced loss aversion and striatal-amygdala coupling in low-anxious individuals
title_short Emotion-induced loss aversion and striatal-amygdala coupling in low-anxious individuals
title_sort emotion-induced loss aversion and striatal-amygdala coupling in low-anxious individuals
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4814785/
https://www.ncbi.nlm.nih.gov/pubmed/26589451
http://dx.doi.org/10.1093/scan/nsv139
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