Lipid-laden cells differentially distributed in the aging brain are functionally active and correspond to distinct phenotypes

We characterized cerebral Oil Red O-positive lipid-laden cells (LLC) of aging mice evaluating their distribution, morphology, density, functional activities and inflammatory phenotype. We identified LLC in meningeal, cortical and neurogenic brain regions. The density of cerebral LLC increased with a...

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Detalles Bibliográficos
Autores principales: Shimabukuro, Marilia Kimie, Langhi, Larissa Gutman Paranhos, Cordeiro, Ingrid, Brito, José M., Batista, Claudia Maria de Castro, Mattson, Mark P., de Mello Coelho, Valeria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4814830/
https://www.ncbi.nlm.nih.gov/pubmed/27029648
http://dx.doi.org/10.1038/srep23795

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