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Connecting the innate and adaptive immune responses in mouse choroidal neovascularization via the anaphylatoxin C5a and γδT-cells

Neovascular age-related macular degeneration (AMD) is characterized by choroidal neovascularization (CNV). An overactive complement system is associated with AMD pathogenesis, and serum pro-inflammatory cytokines, including IL-17, are elevated in AMD patients. IL-17 is produced by complement C5a-rec...

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Detalles Bibliográficos
Autores principales:	Coughlin, Beth, Schnabolk, Gloriane, Joseph, Kusumam, Raikwar, Himanshu, Kunchithapautham, Kannan, Johnson, Krista, Moore, Kristi, Wang, Yi, Rohrer, Bärbel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4814842/ https://www.ncbi.nlm.nih.gov/pubmed/27029558 http://dx.doi.org/10.1038/srep23794

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