Overcoming Hypoxia-Mediated Tumor Progression: Combinatorial Approaches Targeting pH Regulation, Angiogenesis and Immune Dysfunction

Hypoxia is an important contributor to the heterogeneity of the microenvironment of solid tumors and is a significant environmental stressor that drives adaptations which are essential for the survival and metastatic capabilities of tumor cells. Critical adaptive mechanisms include altered metabolis...

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Detalles Bibliográficos
Autores principales: McDonald, Paul C., Chafe, Shawn C., Dedhar, Shoukat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4814851/
https://www.ncbi.nlm.nih.gov/pubmed/27066484
http://dx.doi.org/10.3389/fcell.2016.00027

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4814851/
https://www.ncbi.nlm.nih.gov/pubmed/27066484
http://dx.doi.org/10.3389/fcell.2016.00027

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