Cargando…

Luminal flow induces NADPH oxidase 4 translocation to the nuclei of thick ascending limbs

Superoxide (O(2) (−)) exerts its physiological actions in part by causing changes in gene transcription. In thick ascending limbs flow‐induced O(2) (−) production is mediated by NADPH oxidase 4 (Nox4) and is dependent on protein kinase C (PKC). Polymerase delta interacting protein 2 (Poldip2) increa...

Descripción completa

Detalles Bibliográficos
Autores principales: Saez, Fara, Hong, Nancy J., Garvin, Jeffrey L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4814881/
https://www.ncbi.nlm.nih.gov/pubmed/27033446
http://dx.doi.org/10.14814/phy2.12724

Ejemplares similares