A key role of PGC‐1α transcriptional coactivator in production of VEGF by a novel angiogenic agent COA‐Cl in cultured human fibroblasts

We previously demonstrated a potent angiogenic effect of a newly developed adenosine‐like agent named COA‐Cl. COA‐Cl exerted tube forming activity in human umbilical vein endothelial cells in the presence of normal human dermal fibroblasts (NHDF). We therefore explored whether and how COA‐Cl modulat...

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Detalles Bibliográficos
Autores principales: Igarashi, Junsuke, Okamoto, Ryuji, Yamashita, Tetsuo, Hashimoto, Takeshi, Karita, Sakiko, Nakai, Kozo, Kubota, Yasuo, Takata, Maki, Yamaguchi, Fuminori, Tokuda, Masaaki, Sakakibara, Norikazu, Tsukamoto, Ikuko, Konishi, Ryoji, Hirano, Katsuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4814893/
https://www.ncbi.nlm.nih.gov/pubmed/27033444
http://dx.doi.org/10.14814/phy2.12742

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