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Long range recognition and selection in IDPs: the interactions of the C-terminus of p53

The C-terminal domain of p53 is an extensively studied IDP, interacting with different partners through multiple distinct conformations. To explore the interplay between preformed structural elements and intrinsic fluctuations in its folding and binding we combine extensive atomistic equilibrium and...

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Detalles Bibliográficos
Autores principales:	Kannan, Srinivasaraghavan, Lane, David P., Verma, Chandra S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4814905/ https://www.ncbi.nlm.nih.gov/pubmed/27030593 http://dx.doi.org/10.1038/srep23750

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