Targeting of tubulin polymerization and induction of mitotic blockage by Methyl 2-(5-fluoro-2-hydroxyphenyl)-1H-benzo[d]imidazole-5-carboxylate (MBIC) in human cervical cancer HeLa cell

BACKGROUND: Microtubule Targeting Agents (MTAs) including paclitaxel, colchicine and vinca alkaloids are widely used in the treatment of various cancers. As with most chemotherapeutic agents, adverse effects and drug resistance are commonly associated with the clinical use of these agents. Methyl 2-...

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Detalles Bibliográficos
Autores principales: Hasanpourghadi, Mohadeseh, Karthikeyan, Chandrabose, Pandurangan, Ashok Kumar, Looi, Chung Yeng, Trivedi, Piyush, Kobayashi, Kinue, Tanaka, Kozo, Wong, Won Fen, Mustafa, Mohd Rais
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4815073/
https://www.ncbi.nlm.nih.gov/pubmed/27030360
http://dx.doi.org/10.1186/s13046-016-0332-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4815073/
https://www.ncbi.nlm.nih.gov/pubmed/27030360
http://dx.doi.org/10.1186/s13046-016-0332-0

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