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Free light chains: potential biomarker and predictor of mortality in alpha-1-antitrypsin deficiency and usual COPD
BACKGROUND: Circulating free light chains (FLCs) can alter neutrophil migration, apoptosis and activation and may be a biomarker of autoimmune disease and adaptive immune system activation. These pathogenic roles could be relevant to lung disease in alpha 1 antitrypsin deficiency (A1ATD) and chronic...
Autores principales: | Hampson, Judith A., Stockley, Robert A., Turner, Alice M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4815123/ https://www.ncbi.nlm.nih.gov/pubmed/27036487 http://dx.doi.org/10.1186/s12931-016-0348-1 |
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