Cargando…

The serine protease prostasin (PRSS8) is a potential biomarker for early detection of ovarian cancer

BACKGROUND: Ovarian cancer (OVC) is the deadliest of all gynecologic cancers, primarily as a consequence of asymptomatic progression. The complex nature of OVC creates challenges for early detection, and there is a lack of specific and sensitive biomarkers suitable for screening and detecting early...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tamir, Ayala, Gangadharan, Anju, Balwani, Sakshi, Tanaka, Takemi, Patel, Ushma, Hassan, Ahmed, Benke, Stephanie, Agas, Agnieszka, D’Agostino, Joseph, Shin, Dayoung, Yoon, Sunghoon, Goy, Andre, Pecora, Andrew, Suh, K. Stephen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4815131/ https://www.ncbi.nlm.nih.gov/pubmed/27036110 http://dx.doi.org/10.1186/s13048-016-0228-9

Ejemplares similares

Sodium retention in nephrotic syndrome is independent of the activation of the membrane-anchored serine protease prostasin (CAP1/PRSS8) and its enzymatic activity
por: Essigke, Daniel, et al.
Publicado: (2022)

Regulation of Adrenal Aldosterone Production by Serine Protease Prostasin
por: Ko, Takehiro, et al.
Publicado: (2010)

The testis-specific serine proteases PRSS44, PRSS46, and PRSS54 are dispensable for male mouse fertility(†)
por: Holcomb, Richard J, et al.
Publicado: (2020)

Ibuprofen regulates the expression and function of membrane-associated serine proteases prostasin and matriptase
por: Chai, Andreas C., et al.
Publicado: (2015)

Distinct Spatiotemporal Expression of Serine Proteases Prss23 and Prss35 in Periimplantation Mouse Uterus and Dispensable Function of Prss35 in Fertility
por: Diao, Honglu, et al.
Publicado: (2013)

The serine protease prostasin regulates hepatic insulin sensitivity by modulating TLR4 signalling
por: Uchimura, Kohei, et al.
Publicado: (2014)

Exosome-Mediated Activation of the Prostasin-Matriptase Serine Protease Cascade in B Lymphoma Cells
por: Chen, Li-Mei, et al.
Publicado: (2023)

Mutations in a novel serine protease PRSS56 in families with nanophthalmos
por: Orr, Andrew, et al.
Publicado: (2011)

Prostasin and hepatocyte growth factor B in factor VIIa generation: Serine protease knockdowns in zebrafish
por: Khandekar, Gauri, et al.
Publicado: (2020)

The epidermal barrier function is dependent on the serine protease CAP1/Prss8
por: Leyvraz, Céline, et al.
Publicado: (2005)

Selective Inhibition of Prostasin in Human Enterocytes by the Integral Membrane Kunitz-Type Serine Protease Inhibitor HAI-2
por: Shiao, Frank, et al.
Publicado: (2017)

Loss of prostasin (PRSS8) in human bladder transitional cell carcinoma cell lines is associated with epithelial-mesenchymal transition (EMT)
por: Chen, Li-Mei, et al.
Publicado: (2009)

Serine Protease PRSS23 Is Upregulated by Estrogen Receptor α and Associated with Proliferation of Breast Cancer Cells
por: Chan, Hau-Shien, et al.
Publicado: (2012)

Intramembrane proteolysis of an extracellular serine protease, epithin/PRSS14, enables its intracellular nuclear function
por: Cho, Youngkyung, et al.
Publicado: (2020)

High expression of serine protease 2 (PRSS2) associated with invasion, metastasis, and proliferation in gastric cancer
por: Qin, Haifeng, et al.
Publicado: (2023)

Protein calorie malnutrition, nutritional intervention and personalized cancer care
por: Gangadharan, Anju, et al.
Publicado: (2017)

Reduced Prostasin (CAP1/PRSS8) Activity Eliminates HAI-1 and HAI-2 Deficiency–Associated Developmental Defects by Preventing Matriptase Activation
por: Szabo, Roman, et al.
Publicado: (2012)

Serine protease PRSS55 is crucial for male mouse fertility via affecting sperm migration and sperm–egg binding
por: Shang, Xuan, et al.
Publicado: (2018)

Serine protease PRSS23 drives gastric cancer by enhancing tumor associated macrophage infiltration via FGF2
por: Qin, Shanshan, et al.
Publicado: (2022)

Kallikrein family proteases KLK6 and KLK7 are potential early detection and diagnostic biomarkers for serous and papillary serous ovarian cancer subtypes
por: Tamir, Ayala, et al.
Publicado: (2014)

A novel actor in antitumoral immunity: The thymus-specific serine protease TSSP/PRSS16 involved in CD4(+) T-cell maturation
por: Brisson, Lydie, et al.
Publicado: (2015)

Identification of MFRP and the secreted serine proteases PRSS56 and ADAMTS19 as part of a molecular network involved in ocular growth regulation
por: Koli, Swanand, et al.
Publicado: (2021)

Prostasin: An Epithelial Sodium Channel Regulator
por: Aggarwal, Shakti, et al.
Publicado: (2013)

Membrane protease prostasin promotes insulin secretion by regulating the epidermal growth factor receptor pathway
por: Ishii, Toshihisa, et al.
Publicado: (2023)

Prss55 but not Prss51 is required for male fertility in mice
por: Kobayashi, Kiyonori, et al.
Publicado: (2020)

Targeting metastatic breast cancer with peptide epitopes derived from autocatalytic loop of Prss14/ST14 membrane serine protease and with monoclonal antibodies
por: Kim, Ki Yeon, et al.
Publicado: (2019)

Protease Serine S1 Family Member 8 (PRSS8) Inhibits Tumor Growth In Vitro and In Vivo in Human Non-Small Cell Lung Cancer
por: Ma, Chaonan, et al.
Publicado: (2017)

Impact of suppression of tumorigenicity 14 (ST14)/serine protease 14 (Prss14) expression analysis on the prognosis and management of estrogen receptor negative breast cancer
por: Kim, Sauryang, et al.
Publicado: (2016)

Association between preeclampsia and prostasin polymorphism in Pakistani females
por: Ejaz, Saima, et al.
Publicado: (2020)

The Prevalence of Cationic Trypsinogen (PRSS1) and Serine Protease Inhibitor, Kazal Type 1 (SPINK1) Gene Mutations in Polish Patients with Alcoholic and Idiopathic Chronic Pancreatitis
por: Gasiorowska, Anita, et al.
Publicado: (2010)

Kidney-Specific Membrane-Bound Serine Proteases CAP1/Prss8 and CAP3/St14 Affect ENaC Subunit Abundances but Not Its Activity
por: Ehret, Elodie, et al.
Publicado: (2023)

The Channel-Activating Protease CAP1/Prss8 Is Required for Placental Labyrinth Maturation
por: Hummler, Edith, et al.
Publicado: (2013)

Expression of prostasin and its inhibitors during colorectal cancer carcinogenesis
por: Selzer-Plon, Joanna, et al.
Publicado: (2009)

Genetic polymorphism of the prostasin gene in hypertensive pregnant Pakistani females
por: Ejaz, Saima, et al.
Publicado: (2021)

Editorial: Serine protease inhibitors and their therapeutic applications
por: Crocetti, Letizia, et al.
Publicado: (2022)

The Polymorphisms at PRSS1-PRSS2 and MORC4 Loci and the Risk of Post-ERCP Pancreatitis
por: Angsuwatcharakon, Phonthep, et al.
Publicado: (2018)

Serine protease PRSS56, a novel cancer-testis antigen activated by DNA hypomethylation, promotes colorectal and gastric cancer progression via PI3K/AKT axis
por: Li, Dandan, et al.
Publicado: (2023)

Conserved function of the matriptase-prostasin proteolytic cascade during epithelial morphogenesis
por: Drees, Leonard, et al.
Publicado: (2019)

Mutations in PRSS1 Put into Perspective
por: Sand, Philipp G.
Publicado: (2014)

Secreted protease PRSS35 suppresses hepatocellular carcinoma by disabling CXCL2-mediated neutrophil extracellular traps
por: Wang, Ting, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_8b1nuioncttuj12o2b4jp4i9v7