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In situ detection of GM1 and GM2 gangliosides using immunohistochemical and immunofluorescent techniques for auxiliary diagnosis of canine and feline gangliosidoses

BACKGROUND: GM1 and GM2 gangliosidoses are progressive neurodegenerative lysosomal storage diseases resulting from the excessive accumulation of GM1 and GM2 gangliosides in the lysosomes, respectively. The diagnosis of gangliosidosis is carried out based on comprehensive findings using various types...

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Detalles Bibliográficos
Autores principales: Kohyama, Moeko, Yabuki, Akira, Ochiai, Kenji, Nakamoto, Yuya, Uchida, Kazuyuki, Hasegawa, Daisuke, Takahashi, Kimimasa, Kawaguchi, Hiroaki, Tsuboi, Masaya, Yamato, Osamu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4815186/
https://www.ncbi.nlm.nih.gov/pubmed/27036194
http://dx.doi.org/10.1186/s12917-016-0691-y