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Plasmodium falciparum chloroquine resistance transporter (PfCRT) isoforms PH1 and PH2 perturb vacuolar physiology

BACKGROUND: Recent work has perfected yeast-based methods for measuring drug transport by the Plasmodium falciparum chloroquine (CQ) resistance transporter (PfCRT). METHODS: The approach relies on inducible heterologous expression of PfCRT in Saccharomyces cerevisiae yeast. In these experiments sele...

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Detalles Bibliográficos
Autores principales:	Callaghan, Paul S., Siriwardana, Amila, Hassett, Matthew R., Roepe, Paul D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4815217/ https://www.ncbi.nlm.nih.gov/pubmed/27036417 http://dx.doi.org/10.1186/s12936-016-1238-1

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