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Elucidating nitric oxide synthase domain interactions by molecular dynamics

Nitric oxide synthase (NOS) is a multidomain enzyme that catalyzes the production of nitric oxide (NO) by oxidizing l‐Arg to NO and L‐citrulline. NO production requires multiple interdomain electron transfer steps between the flavin mononucleotide (FMN) and heme domain. Specifically, NADPH‐derived e...

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Detalles Bibliográficos
Autores principales:	Hollingsworth, Scott A., Holden, Jeffrey K., Li, Huiying, Poulos, Thomas L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2015
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4815339/ https://www.ncbi.nlm.nih.gov/pubmed/26448477 http://dx.doi.org/10.1002/pro.2824

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