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Distribution of single‐nucleotide variants on protein–protein interaction sites and its relationship with minor allele frequency
Recent advances in DNA sequencing techniques have identified rare single‐nucleotide variants with less than 1% minor allele frequency. Despite the growing interest and physiological importance of rare variants in genome sciences, less attention has been paid to the allele frequency of variants in pr...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4815344/ https://www.ncbi.nlm.nih.gov/pubmed/26580303 http://dx.doi.org/10.1002/pro.2845 |