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Endothelin
The endothelins comprise three structurally similar 21-amino acid peptides. Endothelin-1 and -2 activate two G-protein coupled receptors, ET(A) and ET(B), with equal affinity, whereas endothelin-3 has a lower affinity for the ET(A) subtype. Genes encoding the peptides are present only among vertebra...
Autores principales: | Davenport, Anthony P., Hyndman, Kelly A., Dhaun, Neeraj, Southan, Christopher, Kohan, Donald E., Pollock, Jennifer S., Pollock, David M., Webb, David J., Maguire, Janet J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Pharmacology and Experimental Therapeutics
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4815360/ https://www.ncbi.nlm.nih.gov/pubmed/26956245 http://dx.doi.org/10.1124/pr.115.011833 |
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