Cargando…

Lung cancer risk at low radon exposure rates in German uranium miners

BACKGROUND: A determination of the risk of lung cancer at low levels of radon exposure is important for occupational radiation protection. METHODS: The risk of death from lung cancer at low radon exposure rates was investigated in the subcohort of 26 766 German uranium miners hired in 1960 or later....

Descripción completa

Detalles Bibliográficos
Autores principales: Kreuzer, M, Fenske, N, Schnelzer, M, Walsh, L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4815799/
https://www.ncbi.nlm.nih.gov/pubmed/26393888
http://dx.doi.org/10.1038/bjc.2015.324
_version_ 1782424630952198144
author Kreuzer, M
Fenske, N
Schnelzer, M
Walsh, L
author_facet Kreuzer, M
Fenske, N
Schnelzer, M
Walsh, L
author_sort Kreuzer, M
collection PubMed
description BACKGROUND: A determination of the risk of lung cancer at low levels of radon exposure is important for occupational radiation protection. METHODS: The risk of death from lung cancer at low radon exposure rates was investigated in the subcohort of 26 766 German uranium miners hired in 1960 or later. RESULTS: A clear association between lung cancer mortality (n=334 deaths) and cumulative exposure to radon in working level months (WLM) was found. The excess relative risk per WLM was 0.013 (95% confidence intervals: 0.007; 0.021). CONCLUSIONS: The present findings provide strong evidence for an increased lung cancer risk after long-term exposure to low radon exposure rates among Wismut miners. The results are compatible to those from residential radon studies and miner studies restricted to low levels.
format Online
Article
Text
id pubmed-4815799
institution National Center for Biotechnology Information
language English
publishDate 2015
publisher Nature Publishing Group
record_format MEDLINE/PubMed
spelling pubmed-48157992016-11-03 Lung cancer risk at low radon exposure rates in German uranium miners Kreuzer, M Fenske, N Schnelzer, M Walsh, L Br J Cancer Epidemiology BACKGROUND: A determination of the risk of lung cancer at low levels of radon exposure is important for occupational radiation protection. METHODS: The risk of death from lung cancer at low radon exposure rates was investigated in the subcohort of 26 766 German uranium miners hired in 1960 or later. RESULTS: A clear association between lung cancer mortality (n=334 deaths) and cumulative exposure to radon in working level months (WLM) was found. The excess relative risk per WLM was 0.013 (95% confidence intervals: 0.007; 0.021). CONCLUSIONS: The present findings provide strong evidence for an increased lung cancer risk after long-term exposure to low radon exposure rates among Wismut miners. The results are compatible to those from residential radon studies and miner studies restricted to low levels. Nature Publishing Group 2015-11-03 2015-09-22 /pmc/articles/PMC4815799/ /pubmed/26393888 http://dx.doi.org/10.1038/bjc.2015.324 Text en Copyright © 2015 Cancer Research UK http://creativecommons.org/licenses/by-nc-sa/4.0/ From twelve months after its original publication, this work is licensed under the Creative Commons Attribution-NonCommercial-Share Alike 4.0 Unported License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-sa/4.0/
spellingShingle Epidemiology
Kreuzer, M
Fenske, N
Schnelzer, M
Walsh, L
Lung cancer risk at low radon exposure rates in German uranium miners
title Lung cancer risk at low radon exposure rates in German uranium miners
title_full Lung cancer risk at low radon exposure rates in German uranium miners
title_fullStr Lung cancer risk at low radon exposure rates in German uranium miners
title_full_unstemmed Lung cancer risk at low radon exposure rates in German uranium miners
title_short Lung cancer risk at low radon exposure rates in German uranium miners
title_sort lung cancer risk at low radon exposure rates in german uranium miners
topic Epidemiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4815799/
https://www.ncbi.nlm.nih.gov/pubmed/26393888
http://dx.doi.org/10.1038/bjc.2015.324
work_keys_str_mv AT kreuzerm lungcancerriskatlowradonexposureratesingermanuraniumminers
AT fensken lungcancerriskatlowradonexposureratesingermanuraniumminers
AT schnelzerm lungcancerriskatlowradonexposureratesingermanuraniumminers
AT walshl lungcancerriskatlowradonexposureratesingermanuraniumminers