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Lung cancer risk at low radon exposure rates in German uranium miners
BACKGROUND: A determination of the risk of lung cancer at low levels of radon exposure is important for occupational radiation protection. METHODS: The risk of death from lung cancer at low radon exposure rates was investigated in the subcohort of 26 766 German uranium miners hired in 1960 or later....
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4815799/ https://www.ncbi.nlm.nih.gov/pubmed/26393888 http://dx.doi.org/10.1038/bjc.2015.324 |
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author | Kreuzer, M Fenske, N Schnelzer, M Walsh, L |
author_facet | Kreuzer, M Fenske, N Schnelzer, M Walsh, L |
author_sort | Kreuzer, M |
collection | PubMed |
description | BACKGROUND: A determination of the risk of lung cancer at low levels of radon exposure is important for occupational radiation protection. METHODS: The risk of death from lung cancer at low radon exposure rates was investigated in the subcohort of 26 766 German uranium miners hired in 1960 or later. RESULTS: A clear association between lung cancer mortality (n=334 deaths) and cumulative exposure to radon in working level months (WLM) was found. The excess relative risk per WLM was 0.013 (95% confidence intervals: 0.007; 0.021). CONCLUSIONS: The present findings provide strong evidence for an increased lung cancer risk after long-term exposure to low radon exposure rates among Wismut miners. The results are compatible to those from residential radon studies and miner studies restricted to low levels. |
format | Online Article Text |
id | pubmed-4815799 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Nature Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-48157992016-11-03 Lung cancer risk at low radon exposure rates in German uranium miners Kreuzer, M Fenske, N Schnelzer, M Walsh, L Br J Cancer Epidemiology BACKGROUND: A determination of the risk of lung cancer at low levels of radon exposure is important for occupational radiation protection. METHODS: The risk of death from lung cancer at low radon exposure rates was investigated in the subcohort of 26 766 German uranium miners hired in 1960 or later. RESULTS: A clear association between lung cancer mortality (n=334 deaths) and cumulative exposure to radon in working level months (WLM) was found. The excess relative risk per WLM was 0.013 (95% confidence intervals: 0.007; 0.021). CONCLUSIONS: The present findings provide strong evidence for an increased lung cancer risk after long-term exposure to low radon exposure rates among Wismut miners. The results are compatible to those from residential radon studies and miner studies restricted to low levels. Nature Publishing Group 2015-11-03 2015-09-22 /pmc/articles/PMC4815799/ /pubmed/26393888 http://dx.doi.org/10.1038/bjc.2015.324 Text en Copyright © 2015 Cancer Research UK http://creativecommons.org/licenses/by-nc-sa/4.0/ From twelve months after its original publication, this work is licensed under the Creative Commons Attribution-NonCommercial-Share Alike 4.0 Unported License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-sa/4.0/ |
spellingShingle | Epidemiology Kreuzer, M Fenske, N Schnelzer, M Walsh, L Lung cancer risk at low radon exposure rates in German uranium miners |
title | Lung cancer risk at low radon exposure rates in German uranium miners |
title_full | Lung cancer risk at low radon exposure rates in German uranium miners |
title_fullStr | Lung cancer risk at low radon exposure rates in German uranium miners |
title_full_unstemmed | Lung cancer risk at low radon exposure rates in German uranium miners |
title_short | Lung cancer risk at low radon exposure rates in German uranium miners |
title_sort | lung cancer risk at low radon exposure rates in german uranium miners |
topic | Epidemiology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4815799/ https://www.ncbi.nlm.nih.gov/pubmed/26393888 http://dx.doi.org/10.1038/bjc.2015.324 |
work_keys_str_mv | AT kreuzerm lungcancerriskatlowradonexposureratesingermanuraniumminers AT fensken lungcancerriskatlowradonexposureratesingermanuraniumminers AT schnelzerm lungcancerriskatlowradonexposureratesingermanuraniumminers AT walshl lungcancerriskatlowradonexposureratesingermanuraniumminers |