Polygenic susceptibility to testicular cancer: implications for personalised health care

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BACKGROUND: The increasing incidence of testicular germ cell tumour (TGCT) combined with its strong heritable basis suggests that stratified screening for the early detection of TGCT may be clinically useful. We modelled the efficiency of such a personalised screening approach, based on genetic risk...

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Detalles Bibliográficos
Autores principales: Litchfield, Kevin, Mitchell, Jonathan S, Shipley, Janet, Huddart, Robert, Rajpert-De Meyts, Ewa, Skakkebæk, Niels E, Houlston, Richard S, Turnbull, Clare
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Genetics & Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4815881/
https://www.ncbi.nlm.nih.gov/pubmed/26461055
http://dx.doi.org/10.1038/bjc.2015.334
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