Downregulation of CDC27 inhibits the proliferation of colorectal cancer cells via the accumulation of p21(Cip1/Waf1)

Dysregulated cell cycle progression has a critical role in tumorigenesis. Cell division cycle 27 (CDC27) is a core subunit of the anaphase-promoting complex/cyclosome, although the specific role of CDC27 in cancer remains unknown. In our study, we explored the biological and clinical significance of...

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Detalles Bibliográficos
Autores principales: Qiu, L, Wu, J, Pan, C, Tan, X, Lin, J, Liu, R, Chen, S, Geng, R, Huang, W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4816181/
https://www.ncbi.nlm.nih.gov/pubmed/26821069
http://dx.doi.org/10.1038/cddis.2015.402

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4816181/
https://www.ncbi.nlm.nih.gov/pubmed/26821069
http://dx.doi.org/10.1038/cddis.2015.402

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