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Overexpression of protein kinase C ɛ improves retention and survival of transplanted mesenchymal stem cells in rat acute myocardial infarction

We assessed the effects of protein kinase C ɛ (PKCɛ) for improving stem cell therapy for acute myocardial infarction (AMI). Primary mesenchymal stem cells (MSCs) were harvested from rat bone marrow. PKCɛ-overexpressed MSCs and control MSCs were transplanted into infarct border zones in a rat AMI mod...

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Detalles Bibliográficos
Autores principales: He, H, Zhao, Z-H, Han, F-S, Liu, X-H, Wang, R, Zeng, Y-J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4816190/
https://www.ncbi.nlm.nih.gov/pubmed/26775707
http://dx.doi.org/10.1038/cddis.2015.417