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Uncovering the Genetic Architectures of Quantitative Traits

The aim of a genome-wide association study (GWAS) is to identify loci in the human genome affecting a phenotype of interest. This review summarizes some recent work on conceptual and methodological aspects of GWAS. The average effect of gene substitution at a given causal site in the genome is the k...

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Detalles Bibliográficos
Autores principales: Lee, James J., Vattikuti, Shashaank, Chow, Carson C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4816193/
https://www.ncbi.nlm.nih.gov/pubmed/27076877
http://dx.doi.org/10.1016/j.csbj.2015.10.002