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Uncovering the Genetic Architectures of Quantitative Traits
The aim of a genome-wide association study (GWAS) is to identify loci in the human genome affecting a phenotype of interest. This review summarizes some recent work on conceptual and methodological aspects of GWAS. The average effect of gene substitution at a given causal site in the genome is the k...
Autores principales: | Lee, James J., Vattikuti, Shashaank, Chow, Carson C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Research Network of Computational and Structural Biotechnology
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4816193/ https://www.ncbi.nlm.nih.gov/pubmed/27076877 http://dx.doi.org/10.1016/j.csbj.2015.10.002 |
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