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Chronic Heavy Alcohol Use is Associated with Upregulated Paneth Cell Antimicrobials in Gastric Mucosa

OBJECTIVES: How alcohol consumption affects the integrity and the defense mechanisms of the mucosa in the upper gastrointestinal tract is largely unknown. We examined the effect of heavy alcohol use on gastric and duodenal Paneth-cell-derived and epithelial antimicrobial peptides (AMPs), cytokines,...

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Detalles Bibliográficos
Autores principales:	Ostaff, M J, Schäfer, C, Courth, L, Stebe, S R D, Ott, G, Stange, E F, Wehkamp, J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2015
Materias:	Original Contributions
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4816256/ https://www.ncbi.nlm.nih.gov/pubmed/26181292 http://dx.doi.org/10.1038/ctg.2015.26

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