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Analysis of the Proteolytic Processing of ABCA3: Identification of Cleavage Site and Involved Proteases

RATIONALE: ABCA3 is a lipid transporter in the limiting membrane of lamellar bodies in alveolar type II cells. Mutations in the ABCA3 gene cause respiratory distress syndrome in new-borns and childhood interstitial lung disease. ABCA3 is N-terminally cleaved by an as yet unknown protease, a process...

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Detalles Bibliográficos
Autores principales:	Hofmann, Nicole, Galetskiy, Dmitry, Rauch, Daniela, Wittmann, Thomas, Marquardt, Andreas, Griese, Matthias, Zarbock, Ralf
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4816274/ https://www.ncbi.nlm.nih.gov/pubmed/27031696 http://dx.doi.org/10.1371/journal.pone.0152594

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