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AZD2014 Radiosensitizes Oral Squamous Cell Carcinoma by Inhibiting AKT/mTOR Axis and Inducing G1/G2/M Cell Cycle Arrest

BACKGROUND: Oral squamous cell carcinoma (OSCC) is one of the most common malignant neoplasms in Taiwan. Activation of the mTOR signaling pathway has been linked to decreased radiation responsiveness in human oral cancer, thus it limits efficacy of radiotherapy. To address this question, we investig...

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Detalles Bibliográficos
Autores principales:	Yu, Chih-Chia, Huang, Hsien-bin, Hung, Shih-Kai, Liao, Hui-Fen, Lee, Ching-Chih, Lin, Hon-Yi, Li, Szu-Chin, Ho, Hsu-Chueh, Hung, Chung-Lin, Su, Yu-Chieh
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4816280/ https://www.ncbi.nlm.nih.gov/pubmed/27031247 http://dx.doi.org/10.1371/journal.pone.0151942

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