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LpMab-12 Established by CasMab Technology Specifically Detects Sialylated O-Glycan on Thr52 of Platelet Aggregation-Stimulating Domain of Human Podoplanin

Podoplanin (PDPN), also known as Aggrus, possesses three tandem repeat of platelet aggregation-stimulating (PLAG) domains in its N-terminus. Among the PLAG domains, sialylated O-glycan on Thr52 of PLAG3 is essential for the binding to C-type lectin-like receptor-2 (CLEC-2) and the platelet-aggregati...

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Detalles Bibliográficos
Autores principales: Kato, Yukinari, Ogasawara, Satoshi, Oki, Hiroharu, Goichberg, Polina, Honma, Ryusuke, Fujii, Yuki, Kaneko, Mika K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4816300/
https://www.ncbi.nlm.nih.gov/pubmed/27031228
http://dx.doi.org/10.1371/journal.pone.0152912

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