The Fifth Domain of Beta 2 Glycoprotein I Protects from Natural IgM Mediated Cardiac Ischaemia Reperfusion Injury

Reperfusion after a period of ischemia results in reperfusion injury (IRI) which involves activation of the inflammatory cascade. In cardiac IRI, IgM natural antibodies (NAb) play a prominent role through binding to altered neoepitopes expressed on damaged cells. Beta 2 Glycoprotein I (β2GPI) is a p...

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Detalles Bibliográficos
Autores principales: Zhang, Peng, Weaver, James C., Chen, Gang, Beretov, Julia, Atsumi, Tatsuya, Qi, Miao, Bhindi, Ravinay, Qi, Jian C., Madigan, Michele C., Giannakopoulos, Bill, Krilis, Steven A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4816326/
https://www.ncbi.nlm.nih.gov/pubmed/27031114
http://dx.doi.org/10.1371/journal.pone.0152681

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