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Endothelin-1 Mediates Brain Microvascular Dysfunction Leading to Long-Term Cognitive Impairment in a Model of Experimental Cerebral Malaria

Plasmodium falciparum infection causes a wide spectrum of diseases, including cerebral malaria, a potentially life-threatening encephalopathy. Vasculopathy is thought to contribute to cerebral malaria pathogenesis. The vasoactive compound endothelin-1, a key participant in many inflammatory processe...

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Detalles Bibliográficos
Autores principales:	Freeman, Brandi D., Martins, Yuri C., Akide-Ndunge, Oscar B., Bruno, Fernando P., Wang, Hua, Tanowitz, Herbert B., Spray, David C., Desruisseaux, Mahalia S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4816336/ https://www.ncbi.nlm.nih.gov/pubmed/27031954 http://dx.doi.org/10.1371/journal.ppat.1005477

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