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System-Wide Associations between DNA-Methylation, Gene Expression, and Humoral Immune Response to Influenza Vaccination

Failure to achieve a protected state after influenza vaccination is poorly understood but occurs commonly among aged populations experiencing greater immunosenescence. In order to better understand immune response in the elderly, we studied epigenetic and transcriptomic profiles and humoral immune r...

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Detalles Bibliográficos
Autores principales: Zimmermann, Michael T., Oberg, Ann L., Grill, Diane E., Ovsyannikova, Inna G., Haralambieva, Iana H., Kennedy, Richard B., Poland, Gregory A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4816338/
https://www.ncbi.nlm.nih.gov/pubmed/27031986
http://dx.doi.org/10.1371/journal.pone.0152034