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Ultra-Deep Sequencing of HIV-1 near Full-Length and Partial Proviral Genomes Reveals High Genetic Diversity among Brazilian Blood Donors

BACKGROUND: Here, we aimed to gain a comprehensive picture of the HIV-1 diversity in the northeast and southeast part of Brazil. To this end, a high-throughput sequencing-by-synthesis protocol and instrument were used to characterize the near full length (NFLG) and partial HIV-1 proviral genome in 2...

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Detalles Bibliográficos
Autores principales: Pessôa, Rodrigo, Loureiro, Paula, Esther Lopes, Maria, Carneiro-Proietti, Anna B. F., Sabino, Ester C, Busch, Michael P., Sanabani, Sabri S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4816342/
https://www.ncbi.nlm.nih.gov/pubmed/27031505
http://dx.doi.org/10.1371/journal.pone.0152499