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Critical Endothelial Regulation by LRP5 during Retinal Vascular Development
Vascular abnormalities in the eye are the leading cause of many forms of inherited and acquired human blindness. Loss-of-function mutations in the Wnt-binding co-receptor LRP5 leads to aberrant ocular vascularization and loss of vision in genetic disorders such as osteoporosis-pseudoglioma syndrome....
Autores principales: | Huang, Wei, Li, Qing, Amiry-Moghaddam, Mahmood, Hokama, Madoka, Sardi, Sylvia H., Nagao, Masashi, Warman, Matthew L., Olsen, Bjorn R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4816525/ https://www.ncbi.nlm.nih.gov/pubmed/27031698 http://dx.doi.org/10.1371/journal.pone.0152833 |
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