Down-Regulation of TLR and JAK/STAT Pathway Genes Is Associated with Diffuse Cutaneous Leishmaniasis: A Gene Expression Analysis in NK Cells from Patients Infected with Leishmania mexicana

An important NK-cell inhibition with reduced TNF-α, IFN-γ and TLR2 expression had previously been identified in patients with diffuse cutaneous leishmaniasis (DCL) infected with Leishmania mexicana. In an attempt to pinpoint alterations in the signaling pathways responsible for the NK-cell dysfuncti...

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Detalles Bibliográficos
Autores principales: Fernández-Figueroa, Edith A., Imaz-Rosshandler, Iván, Castillo-Fernández, Juan E., Miranda-Ortíz, Haydee, Fernández-López, Juan C., Becker, Ingeborg, Rangel-Escareño, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4816531/
https://www.ncbi.nlm.nih.gov/pubmed/27031998
http://dx.doi.org/10.1371/journal.pntd.0004570

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