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Crystallographic Study of Peptidoglycan Biosynthesis Enzyme MurD: Domain Movement Revisited
The biosynthetic pathway of peptidoglycan, an essential component of bacterial cell wall, is a well-recognized target for antibiotic development. Peptidoglycan precursors are synthesized in the bacterial cytosol by various enzymes including the ATP-hydrolyzing Mur ligases, which catalyze the stepwis...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4816537/ https://www.ncbi.nlm.nih.gov/pubmed/27031227 http://dx.doi.org/10.1371/journal.pone.0152075 |