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EGCG Inhibited Lipofuscin Formation Based on Intercepting Amyloidogenic β-Sheet-Rich Structure Conversion
BACKGROUND: Lipofuscin (LF) is formed during lipid peroxidation and sugar glycosylation by carbonyl-amino crosslinks with biomacrolecules, and accumulates slowly within postmitotic cells. The environmental pollution, modern dietary culture and lifestyle changes have been found to be the major source...
Autores principales: | Cai, Shuxian, Yang, Heng, Zeng, Kewu, Zhang, Jing, Zhong, Ni, Wang, Yingzi, Ye, Jing, Tu, Pengfei, Liu, Zhonghua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4816542/ https://www.ncbi.nlm.nih.gov/pubmed/27030967 http://dx.doi.org/10.1371/journal.pone.0152064 |
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