Fatty Acid Oxidation is Impaired in An Orthologous Mouse Model of Autosomal Dominant Polycystic Kidney Disease

BACKGROUND: The major gene mutated in autosomal dominant polycystic kidney disease was first identified over 20 years ago, yet its function remains poorly understood. We have used a systems-based approach to examine the effects of acquired loss of Pkd1 in adult mouse kidney as it transitions from no...

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Detalles Bibliográficos
Autores principales: Menezes, Luis F., Lin, Cheng-Chao, Zhou, Fang, Germino, Gregory G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4816756/
https://www.ncbi.nlm.nih.gov/pubmed/27077126
http://dx.doi.org/10.1016/j.ebiom.2016.01.027

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