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The rapid antidepressant effect of ketamine in rats is associated with down-regulation of pro-inflammatory cytokines in the hippocampus
Objectives. Active inflammatory responses play an important role in the pathogenesis of depression. We hypothesized that the rapid antidepressant effect of ketamine is associated with the down-regulation of pro-inflammatory mediators. Methods. Forty-eight rats were equally randomized into six groups...
Autores principales: | Wang, Nan, Yu, Hai-Ying, Shen, Xiao-Feng, Gao, Zhi-Qin, Yang, Chun, Yang, Jian-Jun, Zhang, Guang-Fen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Informa Healthcare
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4816884/ https://www.ncbi.nlm.nih.gov/pubmed/26220286 http://dx.doi.org/10.3109/03009734.2015.1060281 |
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