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Identification of a major IP(5) kinase in Cryptococcus neoformans confirms that PP-IP(5)/IP(7), not IP(6), is essential for virulence
Fungal inositol polyphosphate (IP) kinases catalyse phosphorylation of IP(3) to inositol pyrophosphate, PP-IP(5)/IP(7), which is essential for virulence of Cryptococcus neoformans. Cryptococcal Kcs1 converts IP(6) to PP-IP(5)/IP(7), but the kinase converting IP(5) to IP(6) is unknown. Deletion of a...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4817067/ https://www.ncbi.nlm.nih.gov/pubmed/27033523 http://dx.doi.org/10.1038/srep23927 |