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Chloroquine increases phosphorylation of AMPK and Akt in myotubes

AIMS: There are reports that ataxia telangiectasia mutated (ATM) can activate the AMP-activated protein kinase (AMPK) and also Akt, two kinases that play integral parts in cardioprotection and metabolic function. We hypothesized that chloroquine and resveratrol, both known ATM activators, would also...

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Detalles Bibliográficos
Autores principales: Spears, Larry D., Tran, Andrew V., Qin, Charles Y., Hobbs, Supriya B., Liang Burns, Cheryl A., Royer, Nathaniel K., Zhang, Zhihong, Ralston, Lyle, Fisher, Jonathan S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4817090/
https://www.ncbi.nlm.nih.gov/pubmed/27047993
http://dx.doi.org/10.1016/j.heliyon.2016.e00083