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Chloroquine increases phosphorylation of AMPK and Akt in myotubes
AIMS: There are reports that ataxia telangiectasia mutated (ATM) can activate the AMP-activated protein kinase (AMPK) and also Akt, two kinases that play integral parts in cardioprotection and metabolic function. We hypothesized that chloroquine and resveratrol, both known ATM activators, would also...
Autores principales: | Spears, Larry D., Tran, Andrew V., Qin, Charles Y., Hobbs, Supriya B., Liang Burns, Cheryl A., Royer, Nathaniel K., Zhang, Zhihong, Ralston, Lyle, Fisher, Jonathan S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4817090/ https://www.ncbi.nlm.nih.gov/pubmed/27047993 http://dx.doi.org/10.1016/j.heliyon.2016.e00083 |
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